Abstinence Assisting Medications - Are they Effective?

ANTABUSE:pain, hyperventilation, tachycardia, and distress. Severe
Antabuse, or disulfiram as it is also known, was thereactions can include respiratory depression,
first medicine approved for the treatment of alcoholcardiovascular collapse, myocardial infarction, acute
abuse and alcohol dependence by the U.S. Food andcongestive heart failure, unconsciousness, arrhythmias,
Drug Administration. It is an "aversive," serving as aconvulsions, and death.
physical and psychological deterrent for someoneCAMPRAL:
trying to stop drinking. It does not reduce the person'sCampral is prescribed as a "post_abstinence" or
craving for alcohol, nor does it treat any alcohol"anti-relapse" support medication. It has no effect on
withdrawal symptoms.cravings, withdrawal, or other early intervention
Research in Europe, where Antabuse is much morediscomforts. The results of European studies seem to
widely used than in the United States, has shown thatindicate a modest positive effect - compared to
long-term use of Antabuse is effective in helping someplacebos - after abstinence has been attained, with
people stop drinking, producing abstinence rates of uprelapse prevention benefits lasting few months. There
to 50 percent. The longer people take Antabuse, theare no such benefits for people seeking to moderate
more effective it is, because they develop a "habit" oftheir alcohol use.
not drinking, which reinforces the establishment ofWhile recommending neither for nor against Campral,
alternative coping skills and behaviors.informed decision making suggests, at this time, a very
While not generally recommending the use ofmodest long-term benefit from Campral in widening a
Antabuse, some individuals find it effective and its useperson's "window of opportunity" for making change.
isn't ruled out completely. If you are contemplating it asFor some individuals even a very small increase in
an option, however, please read the following veryresults is enough reason to seek medical assistance.
carefully and discuss the possibilities with yourAgain, individual responses to medications vary greatly
physician.and you should explore what works best for you.
Antabuse works by interfering with theEven Campral's manufacturers note that it's
ac12;s usual metabolic processing of alcohol into toxiceffectiveness is directly related to participation in
acetaldehyde then into harmless acetic acid. Becauseongoing counseling.
of this, a build up of acetaldehyde five or 10 timesThere are no magic cures, no pills, for alcohol related
greater than normally occurs when someone drinksproblems, only opportunities for change. Success
alcohol. These high concentrations can cause reactionsinvolves coordinated efforts in a variety of areas over
that range from mild to severe, depending on howa year or more, and poor planning will always be
much Antabuse and how much alcohol is consumed,expensive in time, money, health, and other costs.
along with individual tolerance of the drug.Pick your method of treating your alcohol related
If you drink while taking Antabuse, you mayconcerns with care, stay focused, and seek qualified
experience flushing, nausea, copious vomiting, sweating,help with a personally compatable philosophy.
thirst, throbbing headaches, respiratory difficulty, chest